Foods (Jun 2023)

Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms

  • Panthakarn Rangsinth,
  • Rajasekharan Sharika,
  • Nattaporn Pattarachotanant,
  • Chatrawee Duangjan,
  • Chamaiphron Wongwan,
  • Chanin Sillapachaiyaporn,
  • Sunita Nilkhet,
  • Nichaporn Wongsirojkul,
  • Anchalee Prasansuklab,
  • Tewin Tencomnao,
  • George Pak-Heng Leung,
  • Siriporn Chuchawankul

DOI
https://doi.org/10.3390/foods12132529
Journal volume & issue
Vol. 12, no. 13
p. 2529

Abstract

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Ergosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that is converted to vitamin D2 under ultraviolet radiation. The pharmacological effects of ergosterol, which include antimicrobial, antioxidant, antimicrobial, anticancer, antidiabetic, anti-neurodegenerative, and other activities, have also been reported. This review aims to provide an overview of the available evidence regarding the pharmacological effects of ergosterol and its underlying mechanisms of action. Their potential benefits and applications are also discussed.

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