Case Reports in Oncology (Nov 2019)

IgG4-Producing MALT Lymphoma in the Renal Hilum

  • Kota Shimokihara,
  • Takashi Kawahara,
  • Ryo Kasahara,
  • Jun Kasuga,
  • Shinpei Sugiura,
  • Ryosuke Tajiri,
  • Hiroji Uemura,
  • Kimio Chiba

DOI
https://doi.org/10.1159/000504699
Journal volume & issue
Vol. 12, no. 3
pp. 880 – 884

Abstract

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IgG4-related disease is diagnosed when both the elevation of the serum IgG4 level and invasion of IgG4-positive interstitial cells and sclerosis to a tumor are noted. Some cases have demonstrated malignant disease. In the head and neck lesion in particular, IgG4-producing mucosa-associated lymphoid tissue (MALT) lymphoma has arisen during the treatment of IgG4-related disease. We herein report the first case of IgG4-producing MALT lymphoma during the treatment of IgG4-related disease in the renal hilum. A 79-year-old man was being followed for autoimmune pancreatitis and IgG4-related sclerosing cholangitis. During follow-up, magnetic resonance cholangiopancreatography detected a mass in the renal hilum, so he was referred to our department for a further examination. Positron emission tomography-computed tomography detected a standard uptake of 9.7, and the tumor size was gradually increasing. Due to these findings, laparoscopic nephro-ureterectomy was performed. A pathological examination revealed IgG4-producing marginal zone B cell lymphoma. We herein report a rare case of IgG4-producing B cell lymphoma in the renal hilum.

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