PLoS ONE (Jan 2015)

Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa.

  • Jennifer R Lim,
  • Neel R Gandhi,
  • Thuli Mthiyane,
  • Koleka Mlisana,
  • Julie Moodley,
  • Prenika Jaglal,
  • Neeshan Ramdin,
  • James C M Brust,
  • Nazir Ismail,
  • Roxana Rustomjee,
  • N Sarita Shah

DOI
https://doi.org/10.1371/journal.pone.0132076
Journal volume & issue
Vol. 10, no. 7
p. e0132076

Abstract

Read online

South Africa is experiencing a widespread drug-resistant tuberculosis epidemic, although data are limited regarding the current situation. This study finds that the extensively drug-resistant tuberculosis (XDR-TB) incidence in KwaZulu-Natal increased to 3.5 cases/100,000 (776 cases) in 2011-2012. XDR-TB cases are widely distributed geographically, with the majority of districts experiencing a rise in incidence.