P-TSA/NaNO2/NaN3 a mild and efficient system for easy and fast conversion of arylamines to azides at room temperature

Abstract

Abstract This article describes easy, fast and efficient method for the diazotization and azidation of different aromatic amines over p-TSOH hydrate, sodium nitrite and sodium azide under mild condition at room temperature. Various aryl amines possessing electron-withdrawing groups or electron-donating groups were converted into the corresponding aryl azides in 75-99% yields. The use of mild reaction conditions, avoiding the use of harmful acids and toxic solvents and short reaction time are advantages of this methodology. The selected catalyst is found to be highly efficient.

Keywords

• p-toluenesulfonic acid
• aryl azides
• diazotization
• sodium azide
• green chemistry