IMMUNOCHEMICAL STUDIES IN A PATIENT WITH WALDEN-STROM'S MACROGLOBULINEMIA

Abstract

Waldenstrom's macroglobulinemia was studied in a 46 year old Iranian male with anemia, bleeding, ecchymose and splenomegaly. The diagnosis of Macroglobulinemia was established by the presence of veryhigh level of IgM paraprotein in sera which was detectable by imrnunoelectrophoresis and rocket immunoelectrophoresis, and by the presence of bone marrow infiltration of plasmoc ytes. Family studies revealed a high IgM level in one of the patient's daughters.