The role of flavonoids in prevention and treatment of selected skin diseases

Abstract

Introduction and objective The skin is the most important external organ, protecting against pathogens, physical and chemical injuries, as well as ultraviolat (UV) radiation. Continuous exposure to UV radiation, allergens, and pollutants, as well as consumption of highly processed foods, all promote the development and exacerbation of skin diseases, which appear highly differentiated. Skin diseases have a significant impact on the patient’s quality of life and psychological well-being, which is why finding effective therapeutic compounds appears to be so important, especially since multiple conditions still remain untreated. The benefits of flavonoids in the management of psoriasis, acne, atopic dermatitis, urticaria, ringworm, and other skin diseases, are discussed in this review. Review methods A search was conducted using PubMed and Google Scholar databases for articles, to assess the effect of flavonoids in the prevention and treatment of skin diseases. Articles in both Polish and English were searched for. To eliminate duplicate works, the bibliography was reviewed. Brief description of the state of knowledge Flavonoids’ antioxidant and photoprotective properties are the primary factors influencing their preventive use in the development of skin diseases. The risk of tumour formation is significantly reduced as a result of these two applications. They hasten the healing of long-lasting wounds and ulcers due to their circulation-stimulating properties. Plants high in flavonoids are used in dressings and poultices. Their extracts are used in creams and solutions to treat and prevent a variety of skin diseases. Summary The antioxidant and anti-inflammatory effects of flavonoids makes them an important reference in the treatment of skin diseases. The advancement of natural medicinal substances is a critical aspect of modern medicine.

Keywords

• atopic dermatitis
• psoriasis
• acne
• flavonoids
• antioxidation