miR-128-3p reduced acute lung injury induced by sepsis via targeting PEL12

Abstract

Acute lung injury (ALI) caused by sepsis is clinically a syndrome, which is featured by damage to the alveolar epithelium and endothelium. In this study, we employed mice models of cecal ligation and puncture (CLP) and primary mice pulmonary microvascular endothelial cells (MPVECs) in vitro to investigate the effect of miR-128-3p in ALI caused by sepsis.

Keywords

• mir-128-3p
• mpvecs
• acute lung injury
• sepsis
• pel12