Memorias do Instituto Oswaldo Cruz (Nov 1997)

Induction of Glutathione S-transferase Activity in Triatoma infestans

  • JL Sívori,
  • N Casabé,
  • EN Zerba,
  • EJ Wood

DOI
https://doi.org/10.1590/s0074-02761997000600013
Journal volume & issue
Vol. 92, no. 6
p. 797

Abstract

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Several synthetic pesticides and allelochemicals used to treat Triatoma infestans adults by topic application showed some degree of cytosolic glutathione S-transferase (GST) induction. General inducers of detoxication systems such as phenobarbital and 3-methylcholantrene topically applied on T. infestans resulted in no GST induction. Meanwhile, general insecticide synergist such as piperonyl butoxide (160 mg/insect) increased the GST-activity in the range of 120-140%. Insects injected with reduced glutathione (300 mg/insect) presented at the forth day elevated GST activity

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