Journal of the Serbian Chemical Society (Feb 2000)

Synthesis and biological activity of some heterocyclic compounds containing quinoxaline and coumarin moieties

  • M. E. ABD EL-FATTAH,
  • I. M. EL-DEEN

Journal volume & issue
Vol. 65, no. 2
pp. 95 – 102

Abstract

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2,3-Dichloroquinoxaline (2) condensed with 7,8-dihydroxy-4-methylcoumarin to give the 1,4-dioxane derivative 4. 2.3-Dichloroquinoxaline (2) reacted with 4-hydroxycoumarin, 7-hydroxy-4-methylcoumarin and acyl hydrazide 13 to give either the 2,3-(dicoumarin-4-yloxy)quinoxaline (6) or the 2,3-di-(4-methylcoumarin-7-yloxy)quinoxaline (7) or the 2-chloro-3-(coumarin-4-yloxy)quinoxaline (8) or the 2-chloro-3-(4-methylcoumarin-7-yloxy) quinoxaline (9) or the ditriazoloquinoxaline 14 or the oxa-diazinoquinoxaline 16, depending on the relative ratios of the reactants and the reaction conditions.

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