Natural Dietary Supplement, Carvacrol, Alleviates LPS-Induced Oxidative Stress, Neurodegeneration, and Depressive-Like Behaviors via the Nrf2/HO-1 Pathway [Retraction]

Abstract

Naeem K, Tariq Al Kury L, Nasar F, et al. J Inflamm Res. 2021;14:1313–1329. At the authors request, the Editor and Publisher of Journal of Inflammation Research wish to retract the published article. The authors became aware of suspected duplicated images in Figures 4 and 5 and requested for the article to be retracted. Specifically, Figure 4B, Bcl-2, Hippocampus, FLX+LPS appears to have been duplicated with the same image for Figure 4C, Caspase-3, Hippocampus, CAR 20+LPS. Figure 5D, TNF-α, Cortex, LPS appears to have been duplicated with the same image for Figure 5D, TNF-α, Cortex, CAR 20+ATRA+LPS. Figure 5D, TNF-α, Cortex, ATRA+LPS appears to have been duplicated with the same image for Figure 5E, p-NFκB, Cortex, ATRA+LPS (which has been flipped). The Editor agreed with the authors retraction request and the authors were notified of this. Our decision-making was informed by our policy on publishing ethics and integrity and the COPE guidelines on retraction. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.

Keywords

• depression
• neuroinflammation
• nrf2 pathway
• lipopolysaccharide
• carvacrol
• neurodegeneration