Lipoprotein lipase

Martin Merkel; Robert H. Eckel; Ira J. Goldberg

Journal of Lipid Research (Dec 2002)

Lipoprotein lipase

Martin Merkel,
Robert H. Eckel,
Ira J. Goldberg

Affiliations

Martin Merkel: Department of Medicine, University of Hamburg, Hamburg, Germany; Department of Medicine, University of Colorado Health Sciences Center, Denver, CO; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY
Robert H. Eckel: Department of Medicine, University of Hamburg, Hamburg, Germany; Department of Medicine, University of Colorado Health Sciences Center, Denver, CO; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY
Ira J. Goldberg: Department of Medicine, University of Hamburg, Hamburg, Germany; Department of Medicine, University of Colorado Health Sciences Center, Denver, CO; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY

Journal volume & issue: Vol. 43, no. 12
pp. 1997 – 2006

Abstract

Read online

Lipoprotein lipase (LPL) regulates the plasma levels of triglyceride and HDL. Three aspects are reviewed. 1) Clinical implications of human LPL gene variations: common mutations and their effects on plasma lipids and coronary heart disease are discussed. 2) LPL actions in the nervous system, liver, and heart: the discussion focuses on LPL and tissue lipid uptake.3) LPL gene regulation: the LPL promoter and its regulatory elements are described.

Published in Journal of Lipid Research

ISSN: 0022-2275 (Print); 1539-7262 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.journals.elsevier.com/journal-of-lipid-research

About the journal

Abstract

Keywords