Journal of Pediatric Critical Care (Jan 2018)
Sepsis definitions - Changing perspectives
Abstract
The evolving changes in the “definition” of sepsis reflect both a new emphasis on precision, needed for research, and an ever-expanding knowledge of its pathophysiology. Even with the recent revision of sepsis definitions, identification of patients with early sepsis remains a significant challenge. Newer definitions and clinical criteria should clarify long-used descriptors and facilitate earlier recognition and more timely management of patients with sepsis or at risk of developing it. This process, however, remains a work in progress.
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