Nature Communications (Jun 2019)

A neurotoxin that specifically targets Anopheles mosquitoes

  • Estefania Contreras,
  • Geoffrey Masuyer,
  • Nadia Qureshi,
  • Swati Chawla,
  • Harpal S. Dhillon,
  • Han Lim Lee,
  • Jianwu Chen,
  • Pål Stenmark,
  • Sarjeet S. Gill

DOI
https://doi.org/10.1038/s41467-019-10732-w
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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So far identified clostridial neurotoxins target vertebrates. Here, Contreras et al. isolate the clostridial-like neurotoxin PMP1 from Paraclostridium bifermentans strains and show that it selectively targets anopheline mosquitoes by targeting mosquito syntaxin.