International Journal of General Medicine (Jul 2021)

Relationship Between Blood Glucose and Hemoglobin A1c Levels and Urinary Incontinence in Women

  • Liu N,
  • Xing L,
  • Mao W,
  • Chen S,
  • Wu J,
  • Xu B,
  • Chen M

Journal volume & issue
Vol. Volume 14
pp. 4105 – 4116

Abstract

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Ning Liu,1 Li Xing,1 Weipu Mao,1– 3 Shuqiu Chen,1 Jianping Wu,1 Bin Xu,1 Ming Chen1– 3 1Department of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, People’s Republic of China; 2Surgical Research Center, Institute of Urology, Southeast University Medical School, Nanjing, 210009, People’s Republic of China; 3Department of Urology, Nanjing Lishui District People’s Hospital, Zhongda Hospital Lishui Branches, Southeast University, Nanjing, 211200, People’s Republic of ChinaCorrespondence: Ming Chen; Weipu MaoDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, No. 87 Dingjiaqiao, Hunan Road, Gulou District, Nanjing, 210009, People’s Republic of ChinaTel/Fax +86-13913009977; +86-18621571327Email [email protected]; [email protected]: The purpose of this study was to evaluate the associations between blood glucose and hemoglobin A1c (HbA1c) levels with the degree of stress urinary incontinence (SUI) and urgency urinary incontinence (UUI) in women.Methods: We conducted a cross-sectional study of female participants in the National Health and Nutrition Examination Survey (NHANES) database between 2007 and 2012. Univariate and multivariate logistic regressions were used to assess the relationship between blood glucose and HbA1c levels and the degree of SUI and UUI.Results: A total of 3821 participants were enrolled in the study, of whom 2421 (63.4%) had no SUI, 1133 (29.7%) had monthly SUI, 267 (7.0%) had weekly SUI; 2883 (75.5%) had no UUI, 735 (19.2%) had monthly UUI, 203 (5.3%) had weekly UUI. The levels of blood glucose and HbA1c were positively correlated with SUI and UUI, and increased with increasing degree of UUI. Multivariate logistic regression showed that there was a positive association between blood HbA1c level and degree of SUI.Conclusion: Our study found that blood glucose and HbA1c levels can be used as indicators of SUI and UUI severity in women.Keywords: blood glucose, hemoglobin A1c, national health and nutrition examination survey, stress urinary incontinence, urgency urinary incontinence

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