Clinical, Cosmetic and Investigational Dermatology (Oct 2021)
A Case Report of Porokeratosis Ptychotropica in a Chinese Man
Abstract
Xinjia Ou,1,* Ping Wang,2,* Wentao Chen,3 Weiwei Wu,2 Jiejie Lu2 1Department of Dermatology, Hainan Wanning People’s Hospital, Wanning, Hainan, People’s Republic of China; 2Department of Dermatology, The Fifth People’s Hospital of Hainan Province, Branch of National Clinical Research Center for Skin and Immune Disease, Haikou, Hainan, People’s Republic of China; 3Department of Dermatology, Hainan Provincial Anning Hospital, Haikou, Hainan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiejie LuDepartment of Dermatology, The Fifth People’s Hospital of Hainan Province, Branch of National Clinical Research Center for Skin and Immune Disease, No. 33, Southern Road of Longkun, Qiongshan District, Haikou, 570206, Hainan, People’s Republic of ChinaTel +86-13519816255Fax +86-898-66729550Email [email protected]: Porokeratosis ptychotropica is a rare form of porokeratosis characterized by dyskeratotic skin lesions around genital area or gluteal cleft. Herein, a case of porokeratosis ptychotropica was reported. The patient was a 35-year-old man, who complained of pruritic papules and plaques in the perianal and buttock region for thirteen years. On examination, well-demarcated brown plaques with a verrucous white surface and multiple satellite papules were located along the gluteal folds and buttocks sparing the anus. Histopathological examination was consistent with porokeratosis. Combined with clinical manifestations and histopathologic changes, the patient was diagnosed as porokeratosis ptychotropica. He was treated with oral acitretin 30mg/d and CO2 laser treatment, but the lesions showed no evident improvement after three months. Although it is not a new case, this condition is an extremely rare one that must be reviewed and emphasized. The dermatologist should keep porokeratosis ptychotropica in mind as one differential diagnosis for pruritic papules in the anogenital region.Keywords: porokeratosis, intergluteal cleft, buttock
