Silver-catalyzed site-selective C(sp3)−H benzylation of ethers with N-triftosylhydrazones

Abstract

A state-of-the-art tool in synthetic organic chemistry is a rhodium diazocarbene species, which despite its flexibility, is derived from expensive and highly reactive species. Here the authors present a methodology for C–H benzylation of ethers via an analogous silver carbene species, obtained from a more common metal and a more stable starting material.