Nature Communications (Jan 2016)

MatP regulates the coordinated action of topoisomerase IV and MukBEF in chromosome segregation

  • Sophie Nolivos,
  • Amy L. Upton,
  • Anjana Badrinarayanan,
  • Julius Müller,
  • Katarzyna Zawadzka,
  • Jakub Wiktor,
  • Amber Gill,
  • Lidia Arciszewska,
  • Emilien Nicolas,
  • David Sherratt

DOI
https://doi.org/10.1038/ncomms10466
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 12

Abstract

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MukBEF, the bacterial structural maintenance of chromosomes complex, is known to associate with origins of replication and topoisomerase IV. Here the authors show an association of MukBEF with MatP and replication termination regions, important for proper sister chromatid decatenation and segregation.