The case of a new sequence type 7 serogroup X Neisseria meningitidis infection in China: may capsular switching change serogroup profile?

Jinren Pan; Pingping Yao; Heng Zhang; Xiaoyu Sun; Hanqing He; Shuyun Xie

doi:10.1016/j.ijid.2014.07.022

International Journal of Infectious Diseases (Dec 2014)

The case of a new sequence type 7 serogroup X Neisseria meningitidis infection in China: may capsular switching change serogroup profile?

Jinren Pan,
Pingping Yao,
Heng Zhang,
Xiaoyu Sun,
Hanqing He,
Shuyun Xie

Affiliations

Jinren Pan: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province 310051, China
Pingping Yao: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province 310051, China
Heng Zhang: Changsha Center for Disease Control and Prevention, Changsha, Hunan Province, China
Xiaoyu Sun: Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province, China
Hanqing He: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province 310051, China
Shuyun Xie: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province 310051, China

DOI: https://doi.org/10.1016/j.ijid.2014.07.022
Journal volume & issue: Vol. 29, no. C
pp. 62 – 64

Abstract

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Neisseria meningitidis remains the leading cause of bacterial meningitis and septicemia worldwide. We describe a case of invasive meningococcal infection caused by serogroup X N. meningitidis with a unique sequence type (ST-7) in China. The strain may have arisen from locally prevalent hypervirulent serogroup A clones by capsular switching events.

Published in International Journal of Infectious Diseases

ISSN: 1201-9712 (Print); 1878-3511 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: http://www.journals.elsevier.com/international-journal-of-infectious-diseases/

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