金属有机骨架固定化脂肪酶的构筑及其催化 制备生物柴油的研究进展Progress on immobilization of lipase on metal organic framework and its catalytic preparation of biodiesel

Abstract

摘要：金属有机骨架（MOF）具有多样性、高比表面积、化学稳定性和易于后修饰等优势，是固定化酶的优良载体。为了促进生物柴油的发展，针对MOF固定化脂肪酶的方法及其在生物柴油生产中的应用进展进行了综述。MOF固定化脂肪酶的方法有物理吸附法、共价结合法、原位包埋法等，采用MOF固定脂肪酶生产生物柴油，在一定程度上降低了生产成本和提高了产率。开发新型的脂肪酶固定化方法及寻求合适的固定化载体是生物柴油发展的关键。 Metal organic framework (MOF) is an excellent carrier for immobilized enzymes due to its advantages of diversity, high specific surface area, chemical stability and easy post-modification. In order to promote the development of biodiesel, the methods of immobilizing lipase on MOF and its application progress on biodiesel preparation process was reviewed. The methods of immobilizing lipase on MOF include physical adsorption, covalent binding, in-situ embedding, etc. The use of MOF to immobilize lipase for biodiesel production has reduced the production cost and improved the yield to a certain extent. The development of novel immobilization methods for lipase and the search for suitable immobilization carriers have become the key to the development of biodiesel.

Keywords

• 脂肪酶；化学修饰；金属有机骨架(mof)；固定化
• lipase； chemical modification； metal organic framework (mof)； immobilization