Vaccines
(Mar 2023)
Tetanus and Diphtheria Seroprotection among Children Younger Than 15 Years in Nigeria, 2018: Who Are the Unprotected Children?
Rania A. Tohme,
Heather M. Scobie,
Oyeladun Okunromade,
Temitope Olaleye,
Faisal Shuaib,
Tunde Jegede,
Ridwan Yahaya,
Ndodo Nnaemeka,
Bola Lawal,
Abiodun Egwuenu,
Nishanth Parameswaran,
Gretchen Cooley,
Qian An,
Melissa Coughlin,
Bassey B. Okposen,
Ifedayo Adetifa,
Omotayo Bolu,
Chikwe Ihekweazu
Affiliations
Rania A. Tohme
Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Heather M. Scobie
Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Oyeladun Okunromade
Nigeria Center for Disease Control, Abuja 900211, Nigeria
Temitope Olaleye
Institute of Human Virology, FCT, Abuja 900211, Nigeria
Faisal Shuaib
National Primary Healthcare Development Agency, Area 11, Garki, Abuja 900247, Nigeria
Tunde Jegede
Nigeria Center for Disease Control, Abuja 900211, Nigeria
Ridwan Yahaya
Nigeria Center for Disease Control, Abuja 900211, Nigeria
Ndodo Nnaemeka
Nigeria Center for Disease Control, Abuja 900211, Nigeria
Bola Lawal
Nigeria Center for Disease Control, Abuja 900211, Nigeria
Abiodun Egwuenu
Nigeria Center for Disease Control, Abuja 900211, Nigeria
Nishanth Parameswaran
Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Gretchen Cooley
Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Qian An
Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Melissa Coughlin
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Bassey B. Okposen
National Primary Healthcare Development Agency, Area 11, Garki, Abuja 900247, Nigeria
Ifedayo Adetifa
Nigeria Center for Disease Control, Abuja 900211, Nigeria
Omotayo Bolu
Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Chikwe Ihekweazu
Nigeria Center for Disease Control, Abuja 900211, Nigeria
DOI
https://doi.org/10.3390/vaccines11030663
Journal volume & issue
Vol. 11,
no. 3
p.
663
Abstract
Read online
Serological surveys provide an objective biological measure of population immunity, and tetanus serological surveys can also assess vaccination coverage. We undertook a national assessment of immunity to tetanus and diphtheria among Nigerian children aged p p < 0.001). Achieving high infant vaccination coverage by targeting specific geographic areas and socio-economic groups and introducing tetanus and diphtheria booster doses in childhood and adolescence are needed to achieve lifelong protection against tetanus and diphtheria and prevent maternal and neonatal tetanus.
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