Penicillin allergy evaluation in hospitalized patients with hematologic malignancy

Vima M. Patel; Brian Chu; Keith W. Hamilton; Cassandra Bellamy; Christina Harker; Joshua S. Bryer; Bridget Shields; Rebecca L. Hirsh; Olajumoke O. Fadugba; Robert G. Micheletti

doi:10.1017/ash.2023.144

Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2023)

Penicillin allergy evaluation in hospitalized patients with hematologic malignancy

Vima M. Patel,
Brian Chu,
Keith W. Hamilton,
Cassandra Bellamy,
Christina Harker,
Joshua S. Bryer,
Bridget Shields,
Rebecca L. Hirsh,
Olajumoke O. Fadugba,
Robert G. Micheletti

Affiliations

Vima M. Patel: ORCiD; Section of Allergy and Immunology, Division of Pulmonary Allergy and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Brian Chu: ORCiD; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Keith W. Hamilton: Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Cassandra Bellamy: Department of Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Christina Harker: Division of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Joshua S. Bryer: Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Bridget Shields: ORCiD; Department of Dermatology, University of Wisconsin, Madison, Wisconsin
Rebecca L. Hirsh: Division of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Olajumoke O. Fadugba: Section of Allergy and Immunology, Division of Pulmonary Allergy and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Robert G. Micheletti: ORCiD; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

DOI: https://doi.org/10.1017/ash.2023.144
Journal volume & issue: Vol. 3

Abstract

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A penicillin allergy testing service (PATS) assessed penicillin allergy in patients with hematologic malignancies; 17 patients who met criteria had negative skin testing. Patients who underwent penicillin challenge passed and were delabeled. Of delabeled patients, 87% received and tolerated β-lactams during follow-up. Providers found the PATS valuable.

Published in Antimicrobial Stewardship & Healthcare Epidemiology

ISSN: 2732-494X (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Medicine: Public aspects of medicine
Website: https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology

About the journal