Efficiency of rehabilitation treatment of patients with post-COVID syndrome

Abstract

Along with the obvious clinical symptoms caused by the reactivity of the cytokine storm syndrome, patients experience extrapulmonary manifestations of COVID-19. A thorough analysis of large arrays of patients showed that residual symptoms in people with microbiological normalization (i. e., with negative results of the SARS-CoV-2 virus as a criterion for the effectiveness of etiotropic treatment) represent a complex of clinical manifestations that have a single etiopathogenesis, and thus the following is formed concept as post-covid syndrome. Post-covid syndrome has become one of the leading consequences of a new coronavirus infection. The physical, cognitive and neuropsychological consequences of the disease are increasingly becoming realistic, and the associated functional limitations may persist long after discharge from the hospital, negatively affecting the quality of life of patients. Modern ideas of a number of foreign scientists about the manifestations and pathogenesis of post-covid syndrome are reduced to the following aspects: symptoms caused by persistent chronic inflammation are combined with the consequences of damage to internal organs and non-specific manifestations of hospitalization and social isolation. One of the evidence of the pathogenesis of post-covid syndrome is the change in biomarkers, which are criteria for impaired cognitive-motor and psycho-cognitive states of coronavirus infection. The article analyzes the practical experience of using programs for the rehabilitation treatment of patients with COVID-19 in outpatient medical organizations, taking into account changes and prediction of further development of post-COVID syndrome based on the dynamics of concentrations of patients' blood biomarkers. Comprehensive rehabilitation treatment of patients with COVID-19, based on the individual selection of not only physical and physiotherapeutic treatment regimens, but also on the use of drugs, especially drugs that stimulate regeneration and repair, will help to avoid many of the negative consequences of the pathology.

Keywords

• rehabilitation treatment
• post-covid syndrome
• neurovascular biomarkers
• physical status
• neuropsychiatric status