Adherence to the Traditional Mediterranean Diet and Human Milk Composition: Rationale, Design, and Subject Characteristics of the MEDIDIET Study

Frontiers in Pediatrics. 2019;7 DOI 10.3389/fped.2019.00066

 

Journal Homepage

Journal Title: Frontiers in Pediatrics

ISSN: 2296-2360 (Online)

Publisher: Frontiers Media S.A.

LCC Subject Category: Medicine: Pediatrics

Country of publisher: Switzerland

Language of fulltext: English

Full-text formats available: PDF, HTML, ePUB, XML

 

AUTHORS


Guido E. Moro (Italian Association of Human Milk Banks (AIBLUD), Milan, Italy)

Enrico Bertino (Neonatal Intensive Care Unit, Department of Public Health and Pediatrics, Università degli Studi di Torino, Turin, Italy)

Francesca Bravi (Laboratory of Medical Statistics, Biometry and Epidemiology G.A. Maccacaro, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy)

Paola Tonetto (Neonatal Intensive Care Unit, Department of Public Health and Pediatrics, Università degli Studi di Torino, Turin, Italy)

Alberto Gatta (TIN-Neonatology Unit, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy)

Pasqua A. Quitadamo (TIN-Neonatology Unit, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy)

Gugliemo Salvatori (Neonatal Intensive Care Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy)

Claudio Profeti (Azienda Ospedaliero Universitaria Meyer di Firenze, Florence, Italy)

Paola Di Nicola (Neonatal Intensive Care Unit, Department of Public Health and Pediatrics, Università degli Studi di Torino, Turin, Italy)

Adriano Decarli (Laboratory of Medical Statistics, Biometry and Epidemiology G.A. Maccacaro, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy)

Monica Ferraroni (Laboratory of Medical Statistics, Biometry and Epidemiology G.A. Maccacaro, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy)

Alessandra Tavani (Laboratory of Medical Statistics, Biometry and Epidemiology G.A. Maccacaro, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy)

Bernd Stahl (Nutricia Research, Department of Human Milk Research and Analytical Science, Utrecht, Netherlands)

Frank Wiens (Nutricia Research, Department of Human Milk Research and Analytical Science, Utrecht, Netherlands)

EDITORIAL INFORMATION

Blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 14 weeks

 

Abstract | Full Text

Introduction: Knowledge about how a lactating woman's diet influences the composition of her breast milk is still very limited. In particular, no study has evaluated the role of adherence to the Mediterranean diet on human milk characteristics.Aim: We carried out an observational study to investigate the influence of mother adherence to a Mediterranean diet on her breast milk composition.Methods: Between 2012 and 2014, 300 healthy mothers, who exclusively breastfed their babies, were enrolled from five centers across Italy. During a visit to the hospital center 6 weeks after childbirth these women were asked to provide a sample of their freshly expressed breast milk and to answer a series of questions on personal characteristics and lifestyle factors. The application of a validated food frequency questionnaire allowed the collection of detailed dietary habits. Milk was collected and then stored until chemical analyses were performed. The study has been registered (Trial Registration: Dutch Trial register NTR3468). Descriptive analyses on baseline characteristics of mothers and babies were carried out on the participants, overall and stratified by center.Results: The participants had a mean age of 33 years (SD = 4.06), and a pre-pregnancy BMI of 22.3 Kg/m2 (SD = 3.22). Forty-seven percent gave birth to their first child, 40% to the second 13% to the third or subsequent child. Babies had a mean birth weight of 3,324 g (DS = 389), and a mean length of 51 cm (SD = 1.94). Fifty-three percent were males.Conclusion: The present work provides the general description and the characteristics of mothers and babies included in the MediDiet study.