Diagnostics (Dec 2021)

The Role of Echocardiography in the Management of Heart Transplant Recipients

  • Daniele Masarone,
  • Michelle Kittleson,
  • Rita Gravino,
  • Fabio Valente,
  • Andrea Petraio,
  • Giuseppe Pacileo

DOI
https://doi.org/10.3390/diagnostics11122338
Journal volume & issue
Vol. 11, no. 12
p. 2338

Abstract

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Transthoracic echocardiography is the primary non-invasive modality for the investigation of heart transplant recipients. It is a versatile tool that provides comprehensive information on cardiac structure and function. Echocardiography is also helpful in diagnosing primary graft dysfunction and evaluating the effectiveness of therapeutic approaches for this condition. In acute rejection, echocardiography is useful with suspected cellular or antibody-mediated rejection, with findings confirmed and quantified by endomyocardial biopsy. For identifying chronic rejection, ultrasound has a more significant role and, in some specific patients (e.g., patients with renal failure), it may offer a role comparable to coronary angiography to identify cardiac allograft vasculopathy. This review highlights the usefulness of echocardiography in evaluating normal graft function and its role in the management of heart transplant recipients.

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