Nature Communications (Nov 2020)
Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
- Yeon Sik Choi,
- Yuan-Yu Hsueh,
- Jahyun Koo,
- Quansan Yang,
- Raudel Avila,
- Buwei Hu,
- Zhaoqian Xie,
- Geumbee Lee,
- Zheng Ning,
- Claire Liu,
- Yameng Xu,
- Young Joong Lee,
- Weikang Zhao,
- Jun Fang,
- Yujun Deng,
- Seung Min Lee,
- Abraham Vázquez-Guardado,
- Iwona Stepien,
- Ying Yan,
- Joseph W. Song,
- Chad Haney,
- Yong Suk Oh,
- Wentai Liu,
- Hong-Joon Yoon,
- Anthony Banks,
- Matthew R. MacEwan,
- Guillermo A. Ameer,
- Wilson Z. Ray,
- Yonggang Huang,
- Tao Xie,
- Colin K. Franz,
- Song Li,
- John A. Rogers
Affiliations
- Yeon Sik Choi
- Center for Bio-Integrated Electronics, Northwestern University
- Yuan-Yu Hsueh
- Department of Bioengineering, University of California, Los Angeles
- Jahyun Koo
- Center for Bio-Integrated Electronics, Northwestern University
- Quansan Yang
- Querrey Simpson Institute for Biotechnology, Northwestern University
- Raudel Avila
- Department of Mechanical Engineering, Northwestern University
- Buwei Hu
- Department of Bioengineering, University of California, Los Angeles
- Zhaoqian Xie
- State Key Laboratory of Structural Analysis for Industrial Equipment, Dalian, University of Technology
- Geumbee Lee
- Center for Bio-Integrated Electronics, Northwestern University
- Zheng Ning
- State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University
- Claire Liu
- Querrey Simpson Institute for Biotechnology, Northwestern University
- Yameng Xu
- Querrey Simpson Institute for Biotechnology, Northwestern University
- Young Joong Lee
- Querrey Simpson Institute for Biotechnology, Northwestern University
- Weikang Zhao
- Department of Bioengineering, University of California, Los Angeles
- Jun Fang
- Department of Bioengineering, University of California, Los Angeles
- Yujun Deng
- Department of Mechanical Engineering, Northwestern University
- Seung Min Lee
- Center for Bio-Integrated Electronics, Northwestern University
- Abraham Vázquez-Guardado
- Center for Bio-Integrated Electronics, Northwestern University
- Iwona Stepien
- Center for Developmental Therapeutics, Chemistry Life Processes Institute, Northwestern University
- Ying Yan
- Department of Neurological Surgery, Washington University School of Medicine
- Joseph W. Song
- Department of Biomedical Engineering, Northwestern University
- Chad Haney
- Center for Advanced Molecular Imaging, Northwestern University
- Yong Suk Oh
- Center for Bio-Integrated Electronics, Northwestern University
- Wentai Liu
- Department of Bioengineering, University of California, Los Angeles
- Hong-Joon Yoon
- Querrey Simpson Institute for Biotechnology, Northwestern University
- Anthony Banks
- Center for Bio-Integrated Electronics, Northwestern University
- Matthew R. MacEwan
- Department of Neurological Surgery, Washington University School of Medicine
- Guillermo A. Ameer
- Department of Biomedical Engineering, Northwestern University
- Wilson Z. Ray
- Department of Neurological Surgery, Washington University School of Medicine
- Yonggang Huang
- Center for Bio-Integrated Electronics, Northwestern University
- Tao Xie
- State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University
- Colin K. Franz
- Regenerative Neurorehabilitation Laboratory, Biologics, Shirley Ryan AbilityLab
- Song Li
- Department of Bioengineering, University of California, Los Angeles
- John A. Rogers
- Center for Bio-Integrated Electronics, Northwestern University
- DOI
- https://doi.org/10.1038/s41467-020-19660-6
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 14
Abstract
Bioresorbable electronic stimulators can deliver electrical stimulation in rodents to enhance functional muscle recovery after nerve injury. Here, the authors present a bioresorbable dynamic covalent polymer that enables reliable, long-lived operation of soft, stretchable devices of this type.
