Sínteses totais das crocacinas A, C e D: novos antibióticos isolados de Chondromyces crocatus e Chondromyces pediculatus Total synthesis of crocacins A, C and D: new antibiotics isolated from Chondromyces crocatus and Chondromyces pediculatus

Abstract

This review describes the endeavors that led to the total synthesis of a novel class of antibiotic compounds: the crocacins A-D. Other aspects such as isolation, structural elucidation as well as the biological activities are also presented.

Keywords

• crocacins A-D
• novel antibiotics
• enantioselective total synthesis