Comparative evaluation of the anti-cariogenic efficacy of Coleus forskohlii root extract, cranberry extract and magnetized water as mouthrinses in 6-12 years old children: An in vivo study

Abstract

Aim: To evaluate and compare the anti-cariogenic efficacy of Coleus forskohlii root extract, cranberry extract and magnetized water as mouthrinses by analysing pH and buffering capacity of saliva and Streptococcus mutans count in 6-12 years old children. Methods: The current study was an in vivo experimental study where 120 children were randomly assigned to four groups of 30 each. Group 1: Coleus forskohlii root extract, Group 2: Cranberry extract, Group 3: Magnetized water, Group 4: Chlorhexidine mouthrinse. Unstimulated saliva was collected and tested for salivary pH, buffering capacity and S. mutans count at 0, 30, 60, and 90 minutes after rinsing and the results were evaluated. Comparison between groups was carried out using one-way ANOVA, independent t test and paired t test. Results: While magnetized water showed the maximum alteration in the salivary pH, Chlorhexidine mouthrinse showed the maximum reduction in the microbial count followed by Coleus forskohlii root extract. All the groups maintained a favourable salivary buffering capacity. Conclusions: Coleus forskohlii root extract, cranberry extract and magnetized water have proven to be effective anti-cariogenic agents and can be used as alternatives to chlorhexidine in improving the oral health with added systemic benefits and minimal side effects.

Keywords

• chlorhexidine
• coleus forskohlii
• mouthwashes
• vaccinium macrocarpon