Molecular Pathways Leading to Induction of Cell Death and Anti-Proliferative Properties by Tacrolimus and mTOR Inhibitors in Liver Cancer Cells

• Elena Navarro-Villarán,
• Patricia de la Cruz-Ojeda,
• Laura Contreras,
• Raúl González,
• María Negrete,
• María A. Rodríguez-Hernández,
• Luís M. Marín-Gómez,
• José M. Álamo-Martínez,
• Antonio Calvo,
• Miguel A. Gómez-Bravo,
• Jesús de la Cruz,
• Javier Padillo,
• Jordi Muntané

Affiliations

Elena Navarro-Villarán

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Networked Biomedical Research Center Hepatic and Digestive Diseases (CIBEREHD o Ciberehd), Instituto de Salud Carlos III, Madrid, Spain

Patricia de la Cruz-Ojeda

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain

Laura Contreras

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Department of Genetics, University of Seville, Seville, Spain

Raúl González

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Networked Biomedical Research Center Hepatic and Digestive Diseases (CIBEREHD o Ciberehd), Instituto de Salud Carlos III, Madrid, Spain

María Negrete

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain

María A. Rodríguez-Hernández

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Networked Biomedical Research Center Hepatic and Digestive Diseases (CIBEREHD o Ciberehd), Instituto de Salud Carlos III, Madrid, Spain

Luís M. Marín-Gómez

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Networked Biomedical Research Center Hepatic and Digestive Diseases (CIBEREHD o Ciberehd), Instituto de Salud Carlos III, Madrid, Spain; Department of General Surgery, Hospital University “Virgen del Rocío”/CSIC/University of Seville/IBiS, Seville, Spain

José M. Álamo-Martínez

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Networked Biomedical Research Center Hepatic and Digestive Diseases (CIBEREHD o Ciberehd), Instituto de Salud Carlos III, Madrid, Spain; Department of General Surgery, Hospital University “Virgen del Rocío”/CSIC/University of Seville/IBiS, Seville, Spain

Antonio Calvo

Department of General Surgery, Hospital University of Puerto Real, Puerto Real, Spain

Miguel A. Gómez-Bravo

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Networked Biomedical Research Center Hepatic and Digestive Diseases (CIBEREHD o Ciberehd), Instituto de Salud Carlos III, Madrid, Spain; Department of General Surgery, Hospital University “Virgen del Rocío”/CSIC/University of Seville/IBiS, Seville, Spain

Jesús de la Cruz

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Department of Genetics, University of Seville, Seville, Spain

Javier Padillo

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Networked Biomedical Research Center Hepatic and Digestive Diseases (CIBEREHD o Ciberehd), Instituto de Salud Carlos III, Madrid, Spain; Department of General Surgery, Hospital University “Virgen del Rocío”/CSIC/University of Seville/IBiS, Seville, Spain

Jordi Muntané

Institute of Biomedicine of Seville (IBiS), Hospital University “Virgen del Rocío”/CSIC/University of Seville, Seville, Spain; Networked Biomedical Research Center Hepatic and Digestive Diseases (CIBEREHD o Ciberehd), Instituto de Salud Carlos III, Madrid, Spain; Department of General Surgery, Hospital University “Virgen del Rocío”/CSIC/University of Seville/IBiS, Seville, Spain