BIO Web of Conferences (Jan 2023)

Study on wound healing effect of low-carbon topical dressings with new green packaging

  • Zhang Chunhong,
  • Liu Junyi,
  • Liang Dong,
  • Mu Xiaohang,
  • Liu Guiming,
  • Feng Jingqiu,
  • Zeng Yiwen,
  • Huang Gaoling,
  • Wu Xianghan,
  • Mei Jiarui,
  • Li Anjie,
  • Liu Xin,
  • Li Dan

DOI
https://doi.org/10.1051/bioconf/20237202006
Journal volume & issue
Vol. 72
p. 02006

Abstract

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In order to verify the effect of the new green and low-carbon hydrogel dressing on promoting wound healing, this project applied a sodium alginate hydrogel dressing product containing Escherichia coli and taro toxin analgesic polypeptide (The specific ingredients of the dressing) to skin wounds in common rats. Effects of the hydrogel dressing on promoting skin wound healing was evaluated by observing the occurrence and frequency of behavioral changes in rats, observing wwhistological sections under a high-power microscope, changes in serum cytokine indicators, and Image J analysis of collagen fiber reconstruction ratios in tissue sections. Through comprehensive evaluation, it can be found that hydrogel dressing has analgesic, anti-inflammatory and anti-infection effects on rat wound surface, and acts on promoting wound healing, promoting the formation of new blood vessels in the damaged skin tissue area, promoting the growth of granulation tissue, and promoting the reconstruction of collagen fibers in wound tissue.