Hearing Loss in a Patient with Waldenstrom Macroglobulinemia Receiving Bortezomib

Abstract

Introduction: We present a case report of hearing loss in a patient with Waldenstrom macroglobulinemia (WM) receiving treatment with bortezomib. Case Presentation: Our patient developed sudden bilateral sensorineural hearing loss after receiving three doses of bortezomib. His hearing loss was irreversible and resulted in a cochlear implant. Conclusion: Hearing loss secondary to bortezomib is a known, but very rare, side effect. Hearing loss secondary to WM is also rare and has been described in case reports.

Keywords

• bortezomib
• hearing loss
• waldenstrom
• deafness
• case report