Equilibrium in the System of Glauconite – Aqueous Solution of Cefepime Hydrochloride

Abstract

The patterns of immobilization of cefepime hydrochloride on glauconite at a temperature of 295 K are established. The isotherm of sorption of cefepime hydrochloride from dilute solutions is described using the Langmuir theory. The values of the maximum capacity of the monolayer and the coefficient of the sorption equilibrium for cefepime hydrochloride are calculated. It is revealed that the monolayer binding of the antibiotic to glauconite is the result of an equivalent exchange with the extra-frame cations of the sorbent. The polymolecular nature of the sorption may be due to the formation of cefepime hydrochloride associates due to hydrogen bonds.

Keywords

• sorption
• glauconite
• cefepime hydrochloride.