Serum Voriconazole Level Variability in Patients with Hematological Malignancies Receiving Voriconazole Therapy

Lalit Saini; Jack T Seki; Deepali Kumar; Eshetu G Atenafu; David EC Cole; Betty YL Wong; Andrea Božović; Joseph M Brandwein

doi:10.1155/2014/214813

Canadian Journal of Infectious Diseases and Medical Microbiology (Jan 2014)

Serum Voriconazole Level Variability in Patients with Hematological Malignancies Receiving Voriconazole Therapy

Lalit Saini,
Jack T Seki,
Deepali Kumar,
Eshetu G Atenafu,
David EC Cole,
Betty YL Wong,
Andrea Božović,
Joseph M Brandwein

Affiliations

Lalit Saini: Division of Hematology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Jack T Seki: Department of Pharmacy, Princess Margaret Cancer Centre, Canada
Deepali Kumar: Transplant Infectious Diseases, Alberta Transplant Institute, Canada
Eshetu G Atenafu: Biostatistics Department, Princess Margaret Cancer Centre, Canada
David EC Cole: Department of Laboratory Medicine and Pathophysiology and Department of Clinical Pathology, University of Toronto, Canada
Betty YL Wong: Department of Clinical Pathology, Sunnybrook Health Sciences Centre, Canada
Andrea Božović: Laboratory Medicine Program, Toronto General Hospital, University Health Network, Canada
Joseph M Brandwein: Division of Hematology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

DOI: https://doi.org/10.1155/2014/214813
Journal volume & issue: Vol. 25, no. 5
pp. 271 – 276

Abstract

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INTRODUCTION: Voriconazole plasma concentrations have been correlated with oral dosing in healthy subjects, but have been poorly characterized in ill patients with hematological malignancies receiving intensive chemotherapy.

Published in Canadian Journal of Infectious Diseases and Medical Microbiology

ISSN: 1712-9532 (Print); 1918-1493 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Science: Microbiology
Website: https://www.hindawi.com/journals/cjidmm/

About the journal