Nasal fluid sample as a reliable matrix for determination of cytokine levels in childhood asthma

Abstract

Childhood asthma is a chronic disease with high incidence worldwide. As a lifelong disease, asthma has episodes. Inflammation continues to occur in the clinical remission of asthma. It can be difficult to diagnose childhood asthma, especially in clinical remission. We hypothesized that some cytokines secreted to nasal fluid from the airway during inflammation might help diagnose clinical remission of asthma. Moreover, sampling nasal fluid is an easy and non-invasive procedure, so it may be a preferable sampling method.

Keywords

• biomarker
• childhood asthma
• cytokines
• immune response
• remission