International Journal of Nephrology and Renovascular Disease (Feb 2024)

25 [OH] Vitamin D and Intact Parathyroid Hormone in Congolese Hemodialysis Patients: Evaluation of KDIGO Targets

  • Mbadu Lelo S,
  • Musungayi Kajingulu FP,
  • Makulo JR,
  • Mayamba Nlandu Y,
  • Busanga Bukabau J,
  • Koso Mbulupasu P,
  • Luzayadio Longo A,
  • Losa Luse JN,
  • Momeme Mokoli V,
  • Kiswaya Sumaili E,
  • Mangani Nseka N

Journal volume & issue
Vol. Volume 17
pp. 71 – 79

Abstract

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Samuel Mbadu Lelo,1,2 François-Pantaléon Musungayi Kajingulu,1,3,4 Jean-Robert Makulo,1,2 Yannick Mayamba Nlandu,1,5 Justine Busanga Bukabau,1,5 Pierre Koso Mbulupasu,1,6 Augustin Luzayadio Longo,1 Jeanine Nina Losa Luse,7 Vieux Momeme Mokoli,1,2 Ernest Kiswaya Sumaili,1 Nazaire Mangani Nseka1 1Hemodialysis Center, Division of Nephrology, Kinshasa University Hospital, Kinshasa, Democratic Republic of the Congo; 2Hemodialysis Center, Ngaliema Medical Center, Kinshasa, Democratic Republic of the Congo; 3Dialysis Center, HJ Hospital, Kinshasa, Democratic Republic of the Congo; 4Department of Internal Medicine, Saint-Joseph Hospital, Kinshasa, Democratic Republic of the Congo; 5Hemodialysis Center, Centre Médical de Kinshasa, Kinshasa, Democratic Republic of the Congo; 6Department of Internal Medicine, Clinique Ngaliema, Kinshasa, Democratic Republic of the Congo; 7Hemodialysis Center, Hôpital Général de Référence de Kinshasa, Kinshasa, Democratic Republic of the CongoCorrespondence: Jean-Robert Makulo, Email [email protected]: Data on 25 [OH] vitamin D and intact parathyroid hormone [iPTH] in hemodialysis patients are very limited in sub-Saharan African countries. The present study aimed to assess the magnitude of hypovitaminosis D, and to evaluate the achievement of iPTH KDIGO 2017 targets among chronic hemodialysis patients followed in Kinshasa.Methods: We conducted a multicenter cross-sectional study in 6 hospitals in Kinshasa. All patients followed on hemodialysis for more than 3 months were included. Hypovitaminosis D was defined as 600 pg/mL), 45% with levels between 16 and 150 pg/mL and 9% a iPTH ≤ 15 pg/mL.Conclusion: Despite a sunny environment, a large proportion of Congolese hemodialysis patients have hypovitaminosis D, in particular a deficiency. Among them, less than half have target iPTH values. These results show the benefit of regular monitoring of these parameters in order to optimize treatment.Keywords: KDIGO targets, hemodialysis, hypovitaminosis D, iPTH

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