Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures

Dirk Lindenblatt; Anna Nickelsen; Violetta M. Applegate; Jennifer Hochscherf; Benedict Witulski; Zouhair Bouaziz; Christelle Marminon; Maria Bretner; Marc Le Borgne; Joachim Jose; Karsten Niefind

doi:10.1021/acsomega.8b03415

ACS Omega (Mar 2019)

Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures

Dirk Lindenblatt,
Anna Nickelsen,
Violetta M. Applegate,
Jennifer Hochscherf,
Benedict Witulski,
Zouhair Bouaziz,
Christelle Marminon,
Maria Bretner,
Marc Le Borgne,
Joachim Jose,
Karsten Niefind

Affiliations

Dirk Lindenblatt: Department für Chemie, Institut für Biochemie, Universität zu Köln, Köln, Germany
Anna Nickelsen: Institut für Pharmazeutische und Medizinische Chemie, Westfälische Wilhelms-Universität Münster, Münster, Germany
Violetta M. Applegate: Department für Chemie, Institut für Biochemie, Universität zu Köln, Köln, Germany
Jennifer Hochscherf: Department für Chemie, Institut für Biochemie, Universität zu Köln, Köln, Germany
Benedict Witulski: Department für Chemie, Institut für Biochemie, Universität zu Köln, Köln, Germany
Zouhair Bouaziz: EA 4446 Bioactive Molecules and Medicinal Chemistry, SFR Santé Lyon-Est CNRS UMS 3453 - INSERM US7, Faculté de Pharmacie-ISPB, Université Claude Bernard Lyon 1, Lyon Cedex 8, France
Christelle Marminon: EA 4446 Bioactive Molecules and Medicinal Chemistry, SFR Santé Lyon-Est CNRS UMS 3453 - INSERM US7, Faculté de Pharmacie-ISPB, Université Claude Bernard Lyon 1, Lyon Cedex 8, France
Maria Bretner: Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland
Marc Le Borgne: EA 4446 Bioactive Molecules and Medicinal Chemistry, SFR Santé Lyon-Est CNRS UMS 3453 - INSERM US7, Faculté de Pharmacie-ISPB, Université Claude Bernard Lyon 1, Lyon Cedex 8, France
Joachim Jose: Institut für Pharmazeutische und Medizinische Chemie, Westfälische Wilhelms-Universität Münster, Münster, Germany
Karsten Niefind: Department für Chemie, Institut für Biochemie, Universität zu Köln, Köln, Germany

DOI: https://doi.org/10.1021/acsomega.8b03415
Journal volume & issue: Vol. 4, no. 3
pp. 5471 – 5478

Abstract

Read online

No abstracts available.

Published in ACS Omega

ISSN: 2470-1343 (Online)
Publisher: American Chemical Society
Country of publisher: United States
LCC subjects: Science: Chemistry
Website: https://pubs.acs.org/journal/acsodf

About the journal