Nature Communications (Apr 2022)

A robust and interpretable machine learning approach using multimodal biological data to predict future pathological tau accumulation

  • Joseph Giorgio,
  • William J. Jagust,
  • Suzanne Baker,
  • Susan M. Landau,
  • Peter Tino,
  • Zoe Kourtzi,
  • Alzheimer’s Disease Neuroimaging Initiative

DOI
https://doi.org/10.1038/s41467-022-28795-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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The authors present a machine learning approach that combines baseline multimodal data to accurately predict individualised trajectories of future pathological tau accumulation at asymptomatic and mildly impaired stages of Alzheimer’s disease.