Arquivo Brasileiro de Medicina Veterinária e Zootecnia (Aug 2024)

Blood and peritoneal lactate in equine colic: application in emergency care and construction of a decision tree

  • A.M.C. Barros,
  • M.M. Camargo,
  • M. Nichi,
  • C.B. Belli

DOI
https://doi.org/10.1590/1678-4162-13210
Journal volume & issue
Vol. 76, no. 5

Abstract

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ABSTRACT The objective of this retrospective study was to determine whether blood lactate (BL) and peritoneal lactate (PL) are correlated with heart rate, BL-to-PL ratio and dehydration severity in horses with colic that died within or survived beyond 24 hours of hospital admission, and to construct decision trees aimed at predicting short-term mortality using machine learning algorithms. Medical records (n = 339) from the database of the Veterinary Hospital of the School of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ-USP) of horses admitted with colic were retrieved. Correlations between variables of interest were investigated using the Pearson’s or the Spearman’s correlation coefficient. The level of significance was set at 5% (p<0.05). Algorithms used belong to the WEKA environment and were compared using the paired t test (p<0.05). Peritoneal lactate values were strongly and negatively (p<0.05) correlated with BL:PL ratio, and moderately and positively (p<0.05) correlated with percentage of dehydration. Two decision trees with more than 80% accuracy in predicting mortality were constructed and can be used to inform clinicians about the probability of survival beyond the first 24 hours of hospitalization.

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