Indian Journal of Endocrinology and Metabolism (Jan 2014)

LDL-cholesterol: Friedewald calculated versus direct measurement-study from a large Indian laboratory database

  • Subramanian Kannan,
  • Shriraam Mahadevan,
  • Bharath Ramji,
  • Muthukumaran Jayapaul,
  • V Kumaravel

DOI
https://doi.org/10.4103/2230-8210.137496
Journal volume & issue
Vol. 18, no. 4
pp. 502 – 504

Abstract

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Background: Validity of Friedewald formula (FF) in patients with serum triglycerides (TGs) 200) underestimates the LDL calculated by FF particularly at LDL values 130 mg/dl. Conclusion: We suggest repeating the LDL by direct assay techniques particularly in patients with TG >200 and when LDL 130. This helps in correctly stratifying the coronary artery diseases′ (CADs′) risk and goals of treatment.

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