mSphere of Influence: Finding a Direction—How Do Mitochondria Know Where To Go?

Abstract

ABSTRACT Lena Pernas works in the field of metabolism of infection. In this mSphere of Influence article, she reflects on how work by Brian Cunniff (B. Cunniff, A. J. McKenzie, N. H. Heintz, and A. K. Howe, Mol Biol Cell 27:2662–2674, 2016, https://doi.org/10.1091/mbc.e16-05-0286) and Thomas Schwarz (G. Pekkurnaz, J. C. Trinidad, X. Wang, D. Kong, and T. L. Schwarz, Cell 158:54–68, 2014, https://doi.org/10.1016/j.cell.2014.06.007) helped her reframe the study of the interaction between a microbe and mitochondria.

Keywords

• host-pathogen interactions
• intracellular parasites
• metabolism
• mitochondria
• mitochondrial dynamics