mBio
(Feb 2021)
A Grad-seq View of RNA and Protein Complexes in Pseudomonas aeruginosa under Standard and Bacteriophage Predation Conditions
Milan Gerovac,
Laura Wicke,
Kotaro Chihara,
Cornelius Schneider,
Rob Lavigne,
Jörg Vogel
Affiliations
Milan Gerovac
ORCiD Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany
Laura Wicke
ORCiD Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany
Kotaro Chihara
Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany
Cornelius Schneider
Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany
Rob Lavigne
ORCiD Laboratory of Gene Technology, KU Leuven, Leuven, Belgium
Jörg Vogel
ORCiD Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany
DOI
https://doi.org/10.1128/mBio.03454-20
Journal volume & issue
Vol. 12,
no. 1
Abstract
Read online
Stable complexes by cellular proteins and RNA molecules lie at the heart of gene regulation and physiology in any bacterium of interest. It is therefore crucial to globally determine these complexes in order to identify and characterize new molecular players and regulation mechanisms.
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