Research progress on the prevention and treatment of HPV infection-related diseases on mucosal sites

Abstract

A number of benign and malignant diseases on the head, neck and urogenital area are associated with human papillomavirus (HPV) infection on mucosal sites. Nowadays, there are many new research findings for the treatment and prevention of these diseases, such as photodynamic therapy, local immunomodulatory therapy, immune checkpoint inhibitors, targeted therapy, preventive and therapeutic vaccines, etc. In this paper, we summarize the diseases related to HPV infection on mucosal sites, and the research progress on its prevention and treatment.

Keywords

• human papillomavirus
• mucous membrane
• immunotherapy
• vaccine
• infection