Antibiotics (Jun 2022)

Prevention of Surgical Site Infections in Neonates and Children: Non-Pharmacological Measures of Prevention

  • Aniello Meoli,
  • Lorenzo Ciavola,
  • Sofia Rahman,
  • Marco Masetti,
  • Tommaso Toschetti,
  • Riccardo Morini,
  • Giulia Dal Canto,
  • Cinzia Auriti,
  • Caterina Caminiti,
  • Elio Castagnola,
  • Giorgio Conti,
  • Daniele Donà,
  • Luisa Galli,
  • Stefania La Grutta,
  • Laura Lancella,
  • Mario Lima,
  • Andrea Lo Vecchio,
  • Gloria Pelizzo,
  • Nicola Petrosillo,
  • Alessandro Simonini,
  • Elisabetta Venturini,
  • Fabio Caramelli,
  • Gaetano Domenico Gargiulo,
  • Enrico Sesenna,
  • Rossella Sgarzani,
  • Claudio Vicini,
  • Mino Zucchelli,
  • Fabio Mosca,
  • Annamaria Staiano,
  • Nicola Principi,
  • Susanna Esposito,
  • on behalf of the Peri-Operative Prophylaxis in Neonatal and Paediatric Age (POP-NeoPed) Study Group

DOI
https://doi.org/10.3390/antibiotics11070863
Journal volume & issue
Vol. 11, no. 7
p. 863

Abstract

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A surgical site infection (SSI) is an infection that occurs in the incision created by an invasive surgical procedure. Although most infections are treatable with antibiotics, SSIs remain a significant cause of morbidity and mortality after surgery and have a significant economic impact on health systems. Preventive measures are essential to decrease the incidence of SSIs and antibiotic abuse, but data in the literature regarding risk factors for SSIs in the pediatric age group are scarce, and current guidelines for the prevention of the risk of developing SSIs are mainly focused on the adult population. This document describes the current knowledge on risk factors for SSIs in neonates and children undergoing surgery and has the purpose of providing guidance to health care professionals for the prevention of SSIs in this population. Our aim is to consider the possible non-pharmacological measures that can be adopted to prevent SSIs. To our knowledge, this is the first study to provide recommendations based on a careful review of the available scientific evidence for the non-pharmacological prevention of SSIs in neonates and children. The specific scenarios developed are intended to guide the healthcare professional in practice to ensure standardized management of the neonatal and pediatric patients, decrease the incidence of SSIs and reduce antibiotic abuse.

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