First study on the efficacy of abamectin in a combined formulation with praziquantel against Aelurostrongylus abstrusus in cats

Abstract

The information about abamectin efficacy in cases of feline aelurostrongylosis is scarce. Six naturally infected cats were treated with combination of abamectin and praziquantel every seven days until two consecutive negative faecal test results. Abamectin was administered at a dose rate of 0.1 mg/kg. For the evaluation of the efficacy, the number of larvae per gram (LPG) was assessed 30 and 60 days after the first treatment by the Baermann’s technique. After the first 4 administrations, a rapid decline in LPG was observed and after the 8th administration, all animals were free of A. abstrusus larvae. Although the results affirm that abamectin may be successfully used in cases of aelurostrogylosis in cats, further clinical studies are needed to validate this pilot investigation.

Keywords

• aelurostrongylus abstrusus
• cats
• abamectin
• macrocyclic lactone