Serum Osteocalcin, Sclerostin and Lipocalin-2 Levels in Adolescent Boys with Obesity over a 12-Week Sprint Interval Training
Marit Salus,
Vallo Tillmann,
Liina Remmel,
Eve Unt,
Evelin Mäestu,
Ülle Parm,
Agnes Mägi,
Maie Tali,
Jaak Jürimäe
Affiliations
Marit Salus
Institute of Sports Sciences and Physiotherapy, Faculty of Medicine, University of Tartu, Ujula 4, 51008 Tartu, Estonia
Vallo Tillmann
Department of Pediatrics, Institute of Clinical Medicine, Faculty of Medicine, University of Tartu, Lunini 6, 50406 Tartu, Estonia
Liina Remmel
Institute of Sports Sciences and Physiotherapy, Faculty of Medicine, University of Tartu, Ujula 4, 51008 Tartu, Estonia
Eve Unt
Department of Sports Medicine and Rehabilitation, Institute of Clinical Medicine, Faculty of Medicine, University of Tartu, Puusepa 1a, 50406 Tartu, Estonia
Evelin Mäestu
Institute of Sports Sciences and Physiotherapy, Faculty of Medicine, University of Tartu, Ujula 4, 51008 Tartu, Estonia
Ülle Parm
Department of Physiotherapy and Environmental Health, Tartu Health Care College, Nooruse 5, 50411 Tartu, Estonia
Agnes Mägi
Sports Medicine and Rehabilitation Clinic, Tartu University Hospital, Puusepa 1a, 50406 Tartu, Estonia
Maie Tali
Department of Sports Medicine and Rehabilitation, Institute of Clinical Medicine, Faculty of Medicine, University of Tartu, Puusepa 1a, 50406 Tartu, Estonia
Jaak Jürimäe
Institute of Sports Sciences and Physiotherapy, Faculty of Medicine, University of Tartu, Ujula 4, 51008 Tartu, Estonia
The aim of the study was to examine the effects of supervised cycling sprint interval training (SIT) on serum osteocalcin, lipocalin-2 and sclerostin levels, and bone mineral characteristics among obese adolescent boys. Untrained obese adolescent boys aged 13.4 ± 0.3 were assigned to either a 12-week SIT group (3 sessions/week), or a non-exercising control group who continued with their habitual everyday life. Serum osteocalcin, lipocalin-2 and sclerostin concentrations, and bone mineral values were assessed before and after intervention. After 12-week intervention, where 14 boys in both groups ended the study, there were no significant differences in serum osteokine levels between the groups after 12 weeks, while whole body bone mineral content and lower limb bone mineral density increased in the SIT group (p p = 0.034), and positively correlated with the change in lipocalin-2 levels (r = 0.57; p = 0.035) in the SIT group. Supervised 12-week SIT intervention improved bone mineral characteristics, but did not change osteocalcin, lipocalin-2 or sclerostin levels in adolescent boys with obesity.
