A quarter of a century fundamental and translational research in perioperative hypersensitivity and anaphylaxis at the Antwerp university hospital, a Belgian Centre of Excellence of the World Allergy Organization

Didier G. Ebo, MD, PhD; Nils Vlaeminck, MD; Marie-Line M. van der Poorten, MD; Jessy Elst, MSc, PhD; Alessandro Toscano, MD; Athina L. Van Gasse, MD, PhD; Margo M. Hagendorens, MD, PhD; Sophie Aerts, MD; Ine Adriaensens, MD; Vera Saldien, MD, PhD; Vito Sabato, MD, PhD

World Allergy Organization Journal (Mar 2023)

A quarter of a century fundamental and translational research in perioperative hypersensitivity and anaphylaxis at the Antwerp university hospital, a Belgian Centre of Excellence of the World Allergy Organization

Didier G. Ebo, MD, PhD,
Nils Vlaeminck, MD,
Marie-Line M. van der Poorten, MD,
Jessy Elst, MSc, PhD,
Alessandro Toscano, MD,
Athina L. Van Gasse, MD, PhD,
Margo M. Hagendorens, MD, PhD,
Sophie Aerts, MD,
Ine Adriaensens, MD,
Vera Saldien, MD, PhD,
Vito Sabato, MD, PhD

Affiliations

Didier G. Ebo, MD, PhD: Faculty of Medicine and Health Science, Department of Immunology – Allergology – Rheumatology, Antwerp University Hospital and the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium; Department of Immunology and Allergology, AZ Jan Palfijn Gent, Ghent, Belgium; Corresponding author. Laboratory of Immunology, University of Antwerp, CDE T5.95 Universiteitsplein 1, 2610 Antwerpen, Belgium. E-mail
Nils Vlaeminck, MD: Faculty of Medicine and Health Science, Department of Immunology – Allergology – Rheumatology, Antwerp University Hospital and the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium; Faculty of Medicine and Health Science, Department of Anaesthesiology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Marie-Line M. van der Poorten, MD: Faculty of Medicine and Health Science, Department of Immunology – Allergology – Rheumatology, Antwerp University Hospital and the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium; Faculty of Medicine and Health Science, Department of Paediatrics, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium
Jessy Elst, MSc, PhD: Faculty of Medicine and Health Science, Department of Immunology – Allergology – Rheumatology, Antwerp University Hospital and the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium
Alessandro Toscano, MD: Faculty of Medicine and Health Science, Department of Immunology – Allergology – Rheumatology, Antwerp University Hospital and the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium; Post-graduate School of Allergology and Clinical Immunology, University of Milan, Milan, Italy
Athina L. Van Gasse, MD, PhD: Faculty of Medicine and Health Science, Department of Immunology – Allergology – Rheumatology, Antwerp University Hospital and the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium; Faculty of Medicine and Health Science, Department of Paediatrics, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium
Margo M. Hagendorens, MD, PhD: Faculty of Medicine and Health Science, Department of Immunology – Allergology – Rheumatology, Antwerp University Hospital and the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium; Faculty of Medicine and Health Science, Department of Paediatrics, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium
Sophie Aerts, MD: Faculty of Medicine and Health Science, Department of Anaesthesiology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Ine Adriaensens, MD: Faculty of Medicine and Health Science, Department of Anaesthesiology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Vera Saldien, MD, PhD: Faculty of Medicine and Health Science, Department of Anaesthesiology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Vito Sabato, MD, PhD: Faculty of Medicine and Health Science, Department of Immunology – Allergology – Rheumatology, Antwerp University Hospital and the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium; Department of Immunology and Allergology, AZ Jan Palfijn Gent, Ghent, Belgium

Journal volume & issue: Vol. 16, no. 3
p. 100759

Abstract

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Perioperative hypersensitivity constitutes an important health issue, with potential dramatic consequences of diagnostic mistakes. However, safe and correct diagnosis is not always straightforward, mainly because of the application of incorrect nomenclature, absence of easy accessible in-vitro/ex-vivo tests and uncertainties associated with the non-irritating skin test concentrations. In this editorial we summarize the time line, seminal findings, and major realizations of 25 years of research on the mechanisms, diagnosis, and management of perioperative hypersensitivity.

Published in World Allergy Organization Journal

ISSN: 1939-4551 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy
Website: https://www.sciencedirect.com/journal/world-allergy-organization-journal

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