Case Reports in Oncology (Apr 2020)

IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation

  • Saaya Yoshida,
  • Taku Fujimura,
  • Kentaro Ohuchi,
  • Yumi Kambayashi,
  • Yuichiro Segawa,
  • Emi Yamazaki,
  • Hisayuki Tono,
  • Toshiya Takahashi,
  • Kenichiro Tsuchiyama,
  • Setsuya Aiba

DOI
https://doi.org/10.1159/000506975
Journal volume & issue
Vol. 13, no. 1
pp. 462 – 467

Abstract

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Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lymphangiosarcoma that correlate with the immunological background of STS patients. In this report, we described two cases of STS developing in patients who underwent radical dissection for cervical cancer, we employed immunohistochemical staining of IL-23 and IL-17.

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