Neural Regeneration Research (Jan 2015)
Encephalic hemodynamic phases in subarachnoid hemorrhage: how to improve the protective effect in patient prognoses
- Marcelo de Lima Oliveira,
- Daniel Silva de Azevedo,
- Milena Krajnyk de Azevedo,
- Ricardo de Carvalho Nogueira,
- Manoel Jacobsen Teixeira,
- Edson Bor-Seng-Shu
Affiliations
- Marcelo de Lima Oliveira
- Daniel Silva de Azevedo
- Milena Krajnyk de Azevedo
- Ricardo de Carvalho Nogueira
- Manoel Jacobsen Teixeira
- Edson Bor-Seng-Shu
- DOI
- https://doi.org/10.4103/1673-5374.156969
- Journal volume & issue
-
Vol. 10,
no. 5
pp. 748 – 752
Abstract
Subarachnoid hemorrhage is frequently associated with poor prognoses. Three different hemodynamic phases were identified during subarachnoid hemorrhage: oligemia, hyperemia, and vasospasm. Each phase is associated with brain metabolic changes. In this review, we correlated the hemodynamic phases with brain metabolism and potential treatment options in the hopes of improving patient prognoses.
Keywords
- active zone stability
- Drosophila
- neuromuscular junction
- dephosphorylation
- Liprin-α
- Syd-1
- PP2A
- GSK-3ß
- living scaffolds
- neural tissue engineering
- cell transplant
- biomaterials
- regeneration
- neurotrauma
- neurodegeneration
- axon pathfinding
- cell migration
- injury
- plasticity
- neurodegenerative disease
- brain
- therapy
- neuron
- microglia
- neural progenitor
- tissue engineering
- neuroregeneration
- repair
- central nervous system
- biomaterial
- regenerative medicine
- nanotechnology
- spinal cord injury
- axonal regeneration
- exosome
- extracellular vesicle
- microRNA
- microvesicle
- nerve gap
- neurite outgrowth
- peripheral nerve injury
- Schwann cell
- stem cell
- hemodynamic phases
- cerebral subarachnoid hemorrhage
- metabolic crises
