Serbian Journal of Experimental and Clinical Research (2018-09-01)

Analysis of Glycodelin Levels Before and After Hysteroscopic Polypectomy in Infertile Patients

  • Sorak Marija,
  • Devic Ana

Journal volume & issue
Vol. 19, no. 3
pp. 247 – 253


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Glycodelin (or placental protein 14) is a glycoprotein located in the glandular and thin epithelium of the endometrium. It is considered an important factor in the implantation process, and its traces can be found in elevated concentrations in the uterine flushing obtained at the time of implantation, while in the proliferative phase of the cycle, its levels are low. A certain concentration has been found to inhibit the binding of spermatozoids to the zona pellucida of the oocites therefore, it effects conception. It has a role in angiogenesis and is in high concentrations in the tissues of both benign and malignant gynaecological tumours.