JACC: Case Reports (Jan 2024)

Resolution of Cardiac Infiltration Following Autologous Stem Cell Transplantation for AL Amyloidosis

  • Kai Yi Wu, MD,
  • Craig R. Butler, MD, MSc,
  • Nowell M. Fine, MD, SM,
  • Christopher Venner, MD,
  • D. Ian Paterson, MD

Journal volume & issue
Vol. 29, no. 1
p. 102142

Abstract

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A 43-year-old man presented with severe heart failure secondary to high-risk light chain cardiac amyloidosis. He underwent chemotherapy and autologous stem cell transplantation with complete hematologic response. Serial cardiac magnetic resonance imaging post-transplant demonstrated gradual normalization of biventricular function and myocardial T1, a surrogate measure of disease burden.

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