Assessment of Serum 25-Hydroxyvitamin D and Its Association in Type 2 Diabetes Mellitus Elderly Patients with Kidney Disease: A Retrospective Cross Sectional Study
Moyad Shahwan,
Nageeb Hassan,
Noor Mazin,
Ammar Jairoun,
Sahab Al Khoja,
Monzer Shahwan,
Osama Najjar,
Tariq Al-Qirim
Affiliations
Moyad Shahwan
Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman P.O. Box 346, United Arab Emirates
Nageeb Hassan
Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman P.O. Box 346, United Arab Emirates
Noor Mazin
Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman P.O. Box 346, United Arab Emirates
Ammar Jairoun
School of Pharmaceutical Sciences, University Sains Malaysia (USM), Pulau Pinang 11500, Malaysia
Sahab Al Khoja
Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman P.O. Box 346, United Arab Emirates
Monzer Shahwan
Diabetes Clinic, AL-Swity Center for Dermatology and Chronic Diseases, Ramallah 972, Palestine
Osama Najjar
General Directorate of Allied Health Professions, Ministry of Health, Nablus 972, Palestine
Tariq Al-Qirim
Faculty of Pharmacy, Al-Zaytoonah University of Jordan, P.O. Box 130, Amman 11733, Jordan
The overall aim of this study is to determine the prevalence of vitamin D deficiency and its association with diabetic nephropathy in elderly patients with type 2 diabetes mellitus. This study is a single center retrospective cross-sectional design conducted at private medical center. The study group included all patients (18 years or older) suffering from type 2 diabetes mellitus that attended the diabetic clinic from September 2019 to January 2021. The main outcome variable is a trough level of (p value n = 220) were male and 51.4% (n = 233) were female. The mean age ± S.D of the patients was 54.5 ± 10.6 years old. Out of 453 diabetic patients, 71.1% (95% CI: 66.9%–75.3%) had vitamin D deficiency (25OHD p 30 mg/g were more likely to have vitamin D deficiency (p 1.8 mg/dL were more likely to have vitamin D deficiency (p < 0.001). The study revealed a high prevalence of vitamin D deficiency in elderly patients with type 2 diabetes mellitus. A significant association was reported between 25-hydroxyvitamin D, e-GFR and Alb: Cr ratio.
